If you’re looking for anime like Loner Life in Another World, you’re in luck! The shows listed below are packed with tried-and-true stories about characters whisked away to fantastical worlds, often starting as underdogs. Plus, they feature overpowered protagonists who begin as weaklings and often find themselves surrounded by a harem of love interests.
So, whether you enjoy watching characters power up, discover their respective worlds, or face off against powerful foes, there are plenty of anime out there that capture that same vibe!
1. Arifureta

If there’s an anime that takes the crown for its similarity to Loner Life in Another World, it has to be Arifureta. Not only does the whole class of students end up in a fantasy world with RPG elements, but the other classmates end up getting cool abilities while the main character is left behind with “lame” powers. Luckily for our protagonist, he becomes overpowered and even acquires a harem of beautiful waifus.
The MC, Hajime Nagumo, is a high school student who gets transported to a fantasy world with his classmates. After being betrayed and left for dead, he uses his unique skills to become incredibly powerful and seek revenge.
2. The Rising of the Shield Hero

Another isekai anime that’s strikingly similar to Loner Life in Another World is The Rising of the Shield Hero. Both main characters are sent to a world that resembles an RPG game, where they start off weak but become overpowered later. To top it off, they both gain loyal female companions along the way.
The Rising of the Shield Hero follows Naofumi Iwatani, who is summoned to a fantasy world as the Shield Hero. However, he faces betrayal and criticism from those around him. As he trains hard and builds a party of loyal companions, he fights against waves of monsters while proving his worth and seeking revenge.
3. The Fruit of Evolution: Before I Knew It, My Life Had It Made

At this point, it feels like every isekai on this list follows the same formula. Of course, The Fruit of Evolution is no exception. Here, you’ll find all the classic elements of isekai: a harem, a protagonist who starts off weak but becomes overpowered later, and a plot that isn’t particularly deep.
In The Fruit of Evolution, Seiichi Hiiragi, an ordinary guy, gets transported to a fantasy world and discovers a mysterious fruit that gives him incredible powers. As he levels up and becomes overpowered, he also attracts a group of beautiful companions and embarks on wild adventures in his new life.
4. Failure Frame: I Became the Strongest and Annihilated Everything With Low-Level Spells

If you enjoyed the trope of a weak protagonist who transforms into an edgy overpowered hero in Loner Life in Another World, then Failure Frame is sure to deliver.
In this anime, a whole class is summoned to a world filled with swords, magic, and monsters, but the loner Touka Mimori ends up with the weakest powers. To make things worse, the goddess and his classmates abandon and banish him. However, he soon discovers that his “weakest spells” are actually very powerful, leading to his rise from being an outcast to becoming the strongest.
5. Tsukimichi -Moonlit Fantasy-

Tsukimichi: Moonlit Fantasy follows Makoto Misumi, an ordinary guy who gets summoned to a fantasy world, only to be rejected by the goddess for not being “heroic” enough. With his unique skills, he sets out on his own adventure, making powerful friends and taking on all sorts of challenges in this new world.
In both series, the MCs start their journey in a new world only to be rejected almost immediately. However, they soon become OP, effortlessly dealing with any threats, and are joined by beautiful girls.
6. Cautious Hero: The Hero Is Overpowered but Overly Cautious

Another isekai anime with an OP protagonist like Loner Life in Another World is Cautious Hero.
The anime revolves around Seiya Ryuuguuin, a hero summoned to save a fantasy world who takes extreme caution in every situation, despite being overpowered. His overly careful approach leads to hilarious and unpredictable outcomes as he prepares for battles that most would consider already won.
7. The World’s Finest Assassin Gets Reincarnated in Another World as an Aristocrat

The World’s Finest Assassin Gets Reincarnated in Another World as an Aristocrat offers a unique twist on the isekai genre by focusing on a skilled assassin who is given a second chance at life in a new world. With so many low-quality isekai out there, it’s a rare gem in the sea of mediocrity.
The series has the type of edginess and action that Loner in Another World fans enjoy. Also, to make things even better, most of the characters receive actual character development.
8. Chillin’ in Another World with Level 2 Cheats

Chillin’ in Another World with Level 2 Cheats is pretty self-explanatory just from its title. In addition to featuring the extremely popular demi-human waifu Fenrys, it follows the classic formula of a hero being summoned only to initially feel powerless. That is, until the protagonist hits level 2 and gains incredible cheat powers!
Much like Loner Life in Another World, Chillin’ in Another World with Level 2 Cheats showcases boys who are summoned to a fantasy world and quickly deemed useless. Yet, they eventually become the strongest individuals in their worlds, adored by many.
9. So I’m a Spider, So What?

Perhaps you enjoy isekai stories where the main characters start weak but gain amazing powers, and character development is what you’re after. If so, then So I’m a Spider, So What? is something you’d love, even though it doesn’t have a harem and features a female protagonist.
The protagonist of this story is a high school girl who is reincarnated as a spider in a fantasy world after a mysterious incident wipes out her class. Don’t expect any noble goals; she just wants to survive!
10. That Time I Got Reincarnated as a Slime

For those who love badass protagonists in isekai, That Time I Got Reincarnated as a Slime should be on your watch list. The twist with Rimuru is that he’s on the monster side rather than the human side. Much like Haruka in Loner Life in Another World, Rimuru evolves from a weakling to an overpowered protagonist.
In this anime, Satoru Mikami is killed and reincarnated as a slime, the weakest species, in a fantasy world. However, he quickly gains powerful abilities and builds a community of monsters while dealing with various challenges.